ghana seed extract

 Lycopene levels has been America's food and nutrition committee (FoodandNutritionBoard InstituteofMedicine, 2000) considered harmless reversible effect. [2] In animal experiments, through the mouth of natural ghana seed extract lycopene median lethal dose (medianlethaldose, LD50) are > 5000 mg/kgBW. 4 weeks for the synthesis of lycopene, lavage the highest dose of 1000 mg/kgBW lavage and 13 weeks 500 mg/kgBW no positive finding. Given 1000 mg/kgBW rats daily doses of lycopene 100 days, or to give 20 mg daily/kgBW lycopene 200 days, did not observe any toxic reaction caused by the subjects content. Feed dog (100 mg/kgBW lycopene 192 days, in addition to the liver and kidney was observed a slight pigmentation, did not observe any toxic effects.
In rat feeding experiment, dose group (50 mg/kgBW) in serum alanine aminotransferase (ALT) alanineaminotransferase, and aspertate aminotransferase (AST) aspartatetransaminase, reduced, and high dose group (250 mg/kgBW) of gynostemma pentaphyllum leaf extract ALT and AST are higher, and after the stop taking 13 weeks, aspertate aminotransferase activity recovered, but cereal third transaminase is only partially restored, to 50 mg/kgBW was not observed harmful effect level (NOAEL NoObservedAdverseEffectLevel). In the use of rats (maximum dose of 3000 mg/kgBW) and rabbit (the highest dose of 2000 mg/kgBW) on the reproductive and developmental toxicity of no positive findings in the study. Lycopene genetic toxicity experiment (micro nuclear test in vivo, TK gene mutation experiment, chromosome aberration test, etc.) showed that it has no mutagenicity.
According to the company's new product database "global" (GNPD), 2003-2010, the global launch of 418 kinds of new products containing lycopene. These products range from food, supplements and cosmetics fields, which contain lycopene supplement is the most popular products.
Health care products and sport supplements
GNPD data show that a total of 177 global contain lycopene supplement a new product. The state food and drug administration (CFDA) can query to, to get the food health word of lycopene 31 kinds of health care products, including jujube seed powder imported health food 2 kinds, other are domestic health care products. The 31 kinds of health care products is mainly used in the anti-oxidation, anti-aging, enhance immunity, regulating blood lipid, etc., there are two of them are tablets, one kind of oil, the rest are capsules.
GNPD data show that contain lycopene skin care has 81 kinds of new products, make-up 51 species. Typical products such as lycopene moisturizer, whitening and anti-aging effect. Domestic products are lycopene whitening essence daub needle, antioxidant, allergy, the whitening effect.
Lycopene as a potential carotenoid compounds, cannot synthesis by oneself, in the human body must through diet supplement so as to obtain, after found that the physiological function of lycopene, the Ly - of Israel.
CoredNaturalProductsIndustriesLtd. Take the lead in development of lycopene product. In addition, the United States Henkel company and Japanese Makhtshim company respectively producing lycopene as the main active ingredient of the drug, its main functions include drop Low blood pressure, to treat high cholesterol, high blood cholesterol and reduce the cancer cells, etc., has a remarkable curative effect. There is rare in the domestic application of lycopene as food or medicine raw materials.
Lycopene can be used as a nutritional supplements to maintain human lutein and zeaxanthin supplements health, the Japanese made of tomato red oil dementholized resin has been widely used in beverage, cold food, meat products, and baked goods. As a result of the special function of the lycopene, it also is development function in the modern sense Made products functional factors, such as antioxidant health capsule, or made into medicinal food cans after compatibility with other medicinal plants.